• PRECISESADS Cross Sectional Clinical Study- over 2000 patients recruited

    PRECISESADS http://www.precisesads.eu/, an IMI funded project, has now recruited over 2000 people into its pan-European cross sectional clinical study of systemic autoimmune diseases such as rheumatoid arthritis and lupus. This milestone means that the project is well on track towards its goal of recruiting a total of 2 500 people from across 9 European countries. Within the project, patients suffering with systemic autoimmune diseases and healthy people are providing blood and urine samples to undergo detailed molecular analysis at several collaborating laboratories. ‘This will allow us to gain a full molecular profile of the patients and (hopefully) allow us to cluster the patients into groups based on their molecular profile instead of their clinical symptoms,’ explains project coordinator Marta Alarcón-Riquelme of GENYO in Spain. ‘This will then allow clinicians to tailor the therapies to the specific pathways to be targeted in a sort of personalised medicine.’

    The project, which started in February 2014, has already fully recruited an earlier clinical study with 304 patients and analysis of this cohort is currently underway. Once completed the latest study will be used to confirm the findings of this earlier discovery work. Finally, a third cohort, which is underway and currently following 212 newly diagnosed patients over 14 months will be analysed to help understand the clinical value of the confirmed findings.

    Recruitment of the last 350 patients into the latest cohort is expected to finish before mid-October.

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